Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485695 | 0.94 | LMNA (0.52) | GAAMAPTKDM4ETHRBLMNA | |
| SCHEMBL6310745 | 0.81 | CA4 (0.42) | GAAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7306942 | 0.80 | CA1 (0.52) | GAAACHEALDH1A1HPGDPRSS1 | |
| SCHEMBL28806666 | 0.79 | CA4 (0.41) | GAAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL28674679 | 0.79 | CA4 (0.41) | GAAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8103713 | 0.79 | SMN1; SMN2 (0.50) | KDM4ELMNAALDH1A1NPC1HPGD | |
| SCHEMBL8101869 | 0.77 | KIF11 (0.53) | LMNAALDH1A1PRSS1ACRKMT2A | |
| SCHEMBL5655838 | 0.75 | LMNA (0.56) | GAAMAPTKDM4ETHRBLMNA | |
| SCHEMBL1401005 | 0.73 | LMNA (0.54) | GAAMAPTKDM4ETHRBLMNA | |
| SCHEMBL16639671 | 0.72 | ACHE (0.65) | GAAMAPTKDM4ETHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121476-A | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0811612-B1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0811612-A1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |