Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.65 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.57 |
| ▸ | ABL1 | P00519 | 5/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22390547 | 0.85 | NPY5R (0.50) | NPY5RCYP11B1CYP11B2ABL1OPRM1 | |
| SCHEMBL14527315 | 0.85 | ABL1 (0.63) | NPY5RCYP11B1CYP11B2ABL1OPRM1 | |
| SCHEMBL23657861 | 0.83 | NPC1 (0.68) | NPY5RCYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL13362351 | 0.83 | NPY5R (0.67) | NPY5RCYP11B1CYP11B2ABL1OPRM1 | |
| SCHEMBL30562384 | 0.83 | NPY5R (0.67) | NPY5RCYP11B1CYP11B2ABL1OPRM1 | |
| SCHEMBL13740924 | 0.80 | NPY5R (0.52) | NPY5RCYP11B1CYP11B2ABL1CYP3A4 | |
| SCHEMBL10059558 | 0.80 | NPY5R (0.49) | NPY5RCYP11B1CYP11B2ABL1OPRM1 | |
| SCHEMBL8103595 | 0.79 | ABL1 (0.54) | NPY5RABL1CHRM5KIF11SCN5A | |
| SCHEMBL21490277 | 0.79 | ROCK2 (0.62) | CYP11B1CYP11B2ABL1OPRM1KCNH2 | |
| SCHEMBL8111753 | 0.79 | KIF11 (0.56) | NPY5RABL1CYP3A4CHRM5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524058-B | Pyrazolo [1,5 a] pyridine compounds and their and its application | 广州艾格生物科技有限公司 | 2018-03-27 | — | — | CN | claimed |
| US-20200275655-A1 | PYRIDINIUM SALT AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2020-09-03 | — | — | US | disclosed |
| CN-106459022-B | The preparation method of antifungal compound | 北卡罗来纳维亚梅特制药公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-105524058-B | Pyrazolo [1,5 a] pyridine compounds and their and its application | 广州艾格生物科技有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-106459022-A | Antifungal compound process | 维亚梅特制药公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106231901-A | Metal enzyme inhibitor compound as antifungal | 美国陶氏益农公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-102725290-B | As the condensed heterocyclic compouds of ion channel modulators | GILEAD SCIENCES, INC. (US) | 2016-03-09 | — | — | CN | disclosed |
| EP-1019410-A1 | SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2000-07-19 | — | — | EP | disclosed |
| US-6060469-A | Spiro-piperidine derivatives and their use as tachykinin antagonists | MERCK SHARP & DOHME LTD. (GB) | 2000-05-09 | — | — | US | disclosed |
| EP-0808305-A1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1997019084-A1 | SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| WO-1996024585-A1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200275655-A1 | PYRIDINIUM SALT AND PEST CONTROL AGENT | PRDX1, KCNQ5, KCNQ1 | NPY5R 82/4885CYP11B1 1997/4885CYP11B2 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.