Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670616 | 0.86 | MGLL (0.41) | KDM2BLMNAMAPTTP53L3MBTL1 | |
| SCHEMBL8109739 | 0.84 | MGLL (0.45) | LMNAMAPTTP53L3MBTL1MGLL | |
| SCHEMBL8147774 | 0.83 | KDM2B (0.55) | KDM2BLMNAMAPTTP53L3MBTL1 | |
| SCHEMBL8149178 | 0.81 | MGLL (0.48) | KDM2BLMNAMAPTTP53L3MBTL1 | |
| SCHEMBL8140788 | 0.81 | ALDH1A1 (0.48) | LMNAMAPTTP53L3MBTL1MGLL | |
| SCHEMBL8103874 | 0.80 | LMNA (0.53) | KDM2BLMNAMAPTTP53L3MBTL1 | |
| SCHEMBL8111407 | 0.80 | LMNA (0.46) | KDM2BLMNAMAPTTP53L3MBTL1 | |
| SCHEMBL8150423 | 0.80 | LMNA (0.45) | LMNAMAPTTP53L3MBTL1MGLL | |
| SCHEMBL7325935 | 0.79 | MGLL (0.46) | KDM2BLMNAMAPTTP53L3MBTL1 | |
| SCHEMBL4671256 | 0.79 | MGLL (0.46) | KDM2BLMNAMAPTTP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |