Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179765 | 0.88 | CYP1A2 (0.42) | CCNE1CDK2DPP4CYP1A2CYP2D6 | |
| SCHEMBL12327804 | 0.85 | HCAR2 (0.40) | NR1I2MLNRSLCO2B1ABCB11ABCB1 | |
| SCHEMBL8152590 | 0.79 | UGT1A1 (0.43) | DPP4NR1I2MLNRSLCO2B1ABCB11 | |
| SCHEMBL2177873 | 0.79 | UGT1A1 (0.43) | DPP4NR1I2MLNRSLCO2B1ABCB11 | |
| SCHEMBL3393562 | 0.79 | UGT1A1 (0.43) | DPP4NR1I2MLNRSLCO2B1ABCB11 | |
| Hydrochloric Acid SCHEMBL1300940 | 0.78 | UGT1A1 (0.43) | DPP4NR1I2MLNRSLCO2B1ABCB11 | |
| Hydrochloric Acid SCHEMBL30018372 | 0.78 | UGT1A1 (0.43) | DPP4NR1I2MLNRSLCO2B1ABCB11 | |
| Hydrochloric Acid SCHEMBL6156798 | 0.78 | UGT1A1 (0.43) | DPP4NR1I2MLNRSLCO2B1ABCB11 | |
| SCHEMBL2179770 | 0.78 | CA12 (0.41) | CCNE1CDK2DPP4CYP1A2CYP2D6 | |
| SCHEMBL17635682 | 0.77 | UGT1A1 (0.49) | DPP4NR1I2MLNRSLCO2B1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980074-A1 | PROCESS FOR PREPARING ATAZANAVIR BISULFATE AND NOVEL FORMS | Bristol-Myers Squibb Holdings Ireland (CH) | 2016-02-03 | — | — | EP | disclosed |
| US-20110269677-A1 | Oligomer-Protease Inhibitor Conjugates | NEKTAR THERAPEUTICS (US) | 2011-11-03 | — | — | US | disclosed |
| EP-2178513-B1 | TABLETED COMPOSITIONS CONTAINING ATAZANAVIR | BRISTOL MYERS SQUIBB CO (US) | 2011-03-30 | — | — | EP | disclosed |
| EP-2178511-B1 | TABLETED COMPOSITIONS CONTAINING ATAZANAVIR | BRISTOL MYERS SQUIBB CO (US) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009002829-A2 | TABLETED COMPOSITIONS CONTAINING ATAZANAVIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009002823-A2 | TABLETED COMPOSITIONS CONTAINING ATAZANAVIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009002821-A2 | TABLETED COMPOSITIONS CONTAINING ATAZANAVIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2005108349-A2 | PROCESS FOR PREPARING ATAZANAVIR BISULFATE AND NOVEL FORMS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269677-A1 | Oligomer-Protease Inhibitor Conjugates | ADAM17, DNPEP, SERPINB1 | CCNE1 1534/4885CDK2 1099/4885DPP4 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.