Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104045 | 0.89 | NPSR1 (0.46) | NPSR1TSHRCYP1A2CYP2C19CCR2 | |
| SCHEMBL8098709 | 0.89 | TRPM8 (0.39) | NPSR1TRPM8 | |
| SCHEMBL8099316 | 0.85 | TACR1 (0.33) | TACR1TRPM8CCNE1CDK2 | |
| SCHEMBL8099351 | 0.84 | RECQL (0.38) | USP2CYP3A4TSHRCYP1A2CYP2D6 | |
| SCHEMBL8105900 | 0.82 | AR (0.41) | CYP1A2CYP2D6UGT8CYP2C19ACACB | |
| SCHEMBL8097690 | 0.81 | TACR1 (0.31) | TACR1 | |
| SCHEMBL8096910 | 0.80 | CASP3 (0.37) | USP2CYP3A4CYP2C9TSHRCYP1A2 | |
| SCHEMBL8099572 | 0.79 | ACACB (0.47) | NPSR1ACACBHSD17B10 | |
| SCHEMBL8107067 | 0.79 | ACACB (0.47) | NPSR1ACACBHSD17B10 | |
| SCHEMBL8105898 | 0.78 | EPHX2 (0.35) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |