Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597627 | 0.92 | — | — | |
| SCHEMBL8481561 | 0.80 | MYC (0.56) | ALDH1A1KDM4EMYCSMN1; SMN2BRD4 | |
| SCHEMBL8097877 | 0.72 | HTT (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL8480846 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EMYCHPGDBRD4 | |
| SCHEMBL69871 | 0.68 | TSHR (0.46) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL9148724 | 0.67 | MAPT (0.48) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL8593864 | 0.64 | SMN1; SMN2 (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL25610037 | 0.63 | KDM4E (0.44) | ALDH1A1KDM4EHPGDSMN1; SMN2BRD4 | |
| SCHEMBL8590523 | 0.63 | KDM4E (0.47) | ALDH1A1KDM4EHPGDBRD4MAPT | |
| SCHEMBL8484934 | 0.63 | MYC (0.56) | ALDH1A1KDM4EMYCSMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096895-A | Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-01 | — | — | US | disclosed |