Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581367 | 0.87 | LMNA (0.39) | LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL5829763 | 0.86 | LMNA (0.73) | LMNAALDH1A1MAPTMAPK1PGR | |
| SCHEMBL7778506 | 0.82 | TSHR (0.50) | LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL6741044 | 0.81 | LMNA (0.64) | LMNAALDH1A1GAAEPHX2MAPT | |
| SCHEMBL7793705 | 0.80 | LMNA (0.54) | LMNAALDH1A1GAAEPHX2MAPT | |
| SCHEMBL2580673 | 0.79 | CYP1A2 (0.47) | ALDH1A1GAAMAPTPGRADORA3 | |
| SCHEMBL304069 | 0.79 | LMNA (0.61) | LMNAALDH1A1GAAEPHX2MAPT | |
| SCHEMBL15391 | 0.79 | LMNA (0.78) | LMNAALDH1A1GAAEPHX2MAPT | |
| SCHEMBL8104259 | 0.79 | LMNA (0.78) | LMNAALDH1A1GAAEPHX2MAPT | |
| SCHEMBL13558629 | 0.79 | ALDH1A1 (0.48) | LMNAALDH1A1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |