Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104635 | 0.87 | LMNA (0.53) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL7778506 | 0.80 | TSHR (0.50) | LMNAALDH1A1 | |
| SCHEMBL27713949 | 0.78 | LMNA (0.57) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL2580673 | 0.77 | CYP1A2 (0.47) | MAPTALDH1A1 | |
| SCHEMBL22412975 | 0.76 | LMNA (0.48) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL13558629 | 0.76 | ALDH1A1 (0.48) | LMNAALDH1A1 | |
| SCHEMBL2580934 | 0.75 | CYP1A2 (0.46) | MAPTALDH1A1 | |
| SCHEMBL8104544 | 0.75 | EPHX2 (0.35) | — | |
| SCHEMBL37411 | 0.75 | ENPEP (0.39) | ENPEPANPEP | |
| SCHEMBL10063486 | 0.75 | LMNA (0.32) | LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048911-B2 | Melanin eliminator preparation | OGA Research, Inc. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | OGA RESEARCH, INC (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20060122100-A1 | Melanin extinguisher | OGA RESEARCH, INCORPORATED (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1547590-A1 | MELANIN EXTINGUISHER | Oga Research, Incorporated (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122100-A1 | Melanin extinguisher | TYR, MC1R, MITF | LMNA 4485/4885ENPEP 314/4885ANPEP 92/4885 |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | TYR, MC1R, MCHR1 | LMNA 3889/4885ENPEP 129/4885ANPEP 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.