SCHEMBL8104848

SCHEMBL8104848

CSCCC(=O)OC(=O)CCSC

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.35
RNPEP Q9H4A4 1/20 0.34
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FOLH1 Q04609 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8104851 0.93 ALDH1A1 (0.50) ALDH1A1TSHRRNPEPNPC1MAPT
SCHEMBL7793662 0.83 DGKA (0.52) ALDH1A1TSHRMAPTTDP1
Iodide SCHEMBL6069090 0.82 DGKA (0.50) ALDH1A1TSHRMAPTTDP1
SCHEMBL857398 0.81
SCHEMBL1448036 0.77
SCHEMBL16172405 0.77 PKM (0.33) ALDH1A1TDP1
SCHEMBL28017653 0.77 HPGD (0.32) ALDH1A1
SCHEMBL28649015 0.75 HDAC1 (0.42) ALDH1A1SMN1; SMN2FOLH1
SCHEMBL14984425 0.75 DGKA (0.43) ALDH1A1MAPTFOLH1TDP1
SCHEMBL17418381 0.75 ALDH1A1 (0.32) ALDH1A1RNPEPNPC1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450440-B2 Method for purifying polymer and polymer MITSUI CHEMICALS, INC. (JP) 2013-05-28 US disclosed
US-20120208976-A1 METHOD FOR PURIFYING POLYMER AND POLYMER MITSUI CHEMICALS, INC (JP) 2012-08-16 US disclosed
US-6117902-A 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) 2000-09-12 US disclosed