Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391737 | 0.82 | MGLL (0.52) | MGLLMEN1KMT2A | |
| SCHEMBL14356016 | 0.82 | MGLL (0.52) | MGLLMEN1KMT2A | |
| SCHEMBL17244098 | 0.82 | ACKR3 (0.48) | CYP3A4CYP3A5ACKR3 | |
| SCHEMBL13391712 | 0.78 | MGLL (0.52) | MGLLMEN1KMT2A | |
| SCHEMBL14356018 | 0.78 | MGLL (0.52) | MGLLMEN1KMT2A | |
| SCHEMBL28188447 | 0.73 | SLC18A3 (0.54) | CYP3A4MGLLACKR3 | |
| SCHEMBL9535683 | 0.73 | KCNH2 (0.45) | CYP3A4MGLLMEN1KMT2ALMNA | |
| SCHEMBL28188448 | 0.71 | SLC18A3 (0.52) | MGLLACKR3 | |
| SCHEMBL211238 | 0.71 | CYP3A4 (0.52) | CYP3A4CYP3A5 | |
| SCHEMBL4673293 | 0.71 | SLC18A3 (0.55) | KMT2AACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |