Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098773 | 0.85 | HSD11B1 (0.50) | — | |
| SCHEMBL8102863 | 0.75 | HSD11B1 (0.38) | — | |
| SCHEMBL8098776 | 0.72 | TSHR (0.39) | SLC6A3POLB | |
| SCHEMBL2747443 | 0.72 | HSD11B1 (0.57) | — | |
| SCHEMBL8214080 | 0.70 | SLC6A3 (0.31) | SLC6A3 | |
| SCHEMBL8097125 | 0.68 | LMNA (0.45) | — | |
| SCHEMBL8089819 | 0.67 | SLC6A3 (0.31) | SLC6A3 | |
| SCHEMBL28814864 | 0.66 | HSD11B1 (0.31) | — | |
| SCHEMBL3308965 | 0.65 | MAOB (0.41) | SLC6A3 | |
| Acetanilide SCHEMBL29173799 | 0.64 | HSD17B10 (0.58) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661271-B1 | AZEPINE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS SIGMA-RECEPTOR LIGANDS | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0661271-A1 | AZEPINE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-07-05 | — | — | EP | disclosed |