Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107583 | 0.86 | NR4A2 (0.46) | NR4A2TSHRLMNAALDH1A1CFTR | |
| SCHEMBL8107147 | 0.83 | ALDH1A1 (0.43) | TSHRLMNAALDH1A1CFTRHSD17B10 | |
| SCHEMBL16070271 | 0.81 | NR4A2 (0.47) | NR4A2TSHRLMNAALDH1A1CFTR | |
| SCHEMBL10362667 | 0.77 | NR4A2 (0.44) | NR4A2TSHRLMNAALDH1A1CFTR | |
| SCHEMBL8097827 | 0.75 | LMNA (0.52) | TSHRLMNAALDH1A1CFTRHSD17B10 | |
| SCHEMBL524457 | 0.73 | LMNA (0.53) | NR4A2TSHRLMNAALDH1A1CFTR | |
| SCHEMBL101601 | 0.73 | TSHR (0.63) | NR4A2TSHRLMNAALDH1A1CFTR | |
| SCHEMBL29702037 | 0.73 | TSHR (0.63) | NR4A2TSHRLMNAALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL28079217 | 0.73 | TSHR (0.63) | NR4A2TSHRLMNAALDH1A1CFTR | |
| SCHEMBL28473965 | 0.73 | NR4A2 (0.49) | NR4A2TSHRLMNAALDH1A1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |