Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105878 | 0.86 | NR4A2 (0.44) | NR4A2LMNATSHRKMT2AMAPT | |
| SCHEMBL8113169 | 0.84 | NR4A2 (0.41) | NR4A2LMNATSHRPKMSLC6A4 | |
| SCHEMBL8107147 | 0.81 | ALDH1A1 (0.43) | LMNATSHRCYP1A2CYP2C19SLC6A4 | |
| SCHEMBL22056275 | 0.77 | NR4A2 (0.44) | NR4A2LMNATSHRPKMCYP1A2 | |
| SCHEMBL8097763 | 0.75 | CYP1A2 (0.38) | LMNATSHRCYP1A2KMT2AMAPT | |
| SCHEMBL8132105 | 0.75 | MAPT (0.47) | NR4A2LMNATSHRPKMSLC6A4 | |
| SCHEMBL30363028 | 0.75 | NR4A2 (0.59) | NR4A2LMNATSHRPKMCYP1A2 | |
| SCHEMBL993113 | 0.74 | TSHR (0.59) | NR4A2LMNATSHRPKMCYP1A2 | |
| SCHEMBL196555 | 0.74 | LMNA (0.61) | NR4A2LMNATSHRSLC6A4SLC6A3 | |
| SCHEMBL30488606 | 0.74 | LMNA (0.61) | NR4A2LMNATSHRSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | claimed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | claimed |
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |