Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003346 | 0.92 | MEN1 (0.50) | POLBMEN1KMT2ALMNAPLIN1 | |
| SCHEMBL27598322 | 0.88 | ALDH1A1 (0.49) | POLBKMT2AHTTNPSR1L3MBTL1 | |
| SCHEMBL29114668 | 0.87 | POLB (0.40) | POLBMEN1KMT2ALMNAPLIN1 | |
| SCHEMBL10727471 | 0.82 | ITGA4 (0.45) | POLBMEN1KMT2ALMNAPLIN1 | |
| SCHEMBL9738865 | 0.81 | CASP1 (0.55) | MEN1KMT2ALMNAMMP8PIN1 | |
| SCHEMBL7057074 | 0.80 | KMT2A (0.43) | POLBMEN1KMT2ALMNAPLIN1 | |
| SCHEMBL22144400 | 0.80 | MEN1 (0.49) | POLBMEN1KMT2ALMNAPLIN1 | |
| SCHEMBL22283800 | 0.80 | MEN1 (0.49) | POLBMEN1KMT2ALMNAPLIN1 | |
| SCHEMBL11263712 | 0.80 | KMT2A (0.49) | POLBMEN1KMT2ALMNAPLIN1 | |
| SCHEMBL1717566 | 0.79 | MMP8 (0.51) | POLBMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942523-B | Benzofuran and benzofuran coumarin derivatives, and preparation method and application thereof | 华东师范大学 | 2023-06-09 | — | — | CN | disclosed |
| US-6046135-A | FOR CONTROLLING WEEDS | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-04-04 | — | — | US | disclosed |
| EP-0866788-A1 | 1,3-OXAZIN-4-ONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997021688-A1 | 1,3-OXAZIN-4-ONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-06-19 | — | — | WO | disclosed |