Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MITF | O75030 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106476 | 0.81 | FGFR1 (0.46) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL8106524 | 0.79 | HSP90AA1 (0.54) | ALDH1A1MAPTLMNAHTTHKDC1 | |
| SCHEMBL8092901 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL8100896 | 0.78 | KMT2A (0.39) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL8092608 | 0.77 | RAB9A (0.55) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL8102266 | 0.77 | HSP90AA1 (0.41) | ALDH1A1MAPTHTTFGFR1FGFR2 | |
| SCHEMBL8108597 | 0.76 | TDP2 (0.61) | ALDH1A1MAPTHTTPOLBFGFR1 | |
| SCHEMBL8102167 | 0.76 | DHODH (0.51) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL8102117 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL8102608 | 0.75 | PTPN1 (0.46) | ALDH1A1MAPTLMNAMITFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |