Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093520 | 1.00 | GLO1 (0.42) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL13242085 | 0.84 | GLO1 (0.45) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL16674850 | 0.81 | GLO1 (0.47) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL16160202 | 0.79 | NPSR1 (0.48) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL12200406 | 0.78 | NPSR1 (0.42) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL17268280 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL6249795 | 0.76 | NPSR1 (0.41) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL10391796 | 0.75 | GLO1 (0.59) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL234358 | 0.74 | NPSR1 (0.59) | GLO1NPSR1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL234359 | 0.74 | NPSR1 (0.59) | GLO1NPSR1ALDH1A1TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184998-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-07-22 | — | — | US | disclosed |
| CN-101679178-A | Process for the synthesis of intermediates of renin inhibitors such as aliskiren | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |
| WO-2008155338-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184998-A1 | ORGANIC COMPOUNDS | CYP1B1, CYP3A7, CYP2F1 | GLO1 1645/4885NPSR1 2294/4885ALDH1A1 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.