Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 1.00 |
| ▸ | FNTB | P49356 | 10/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 9/20 | 1.00 |
| ▸ | ANPEP | P15144 | 2/20 | 0.58 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.58 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111003 | 0.82 | FNTA (1.00) | FNTAFNTBPGGT1BANPEPENPEP | |
| SCHEMBL8097474 | 0.79 | FNTA (1.00) | FNTAFNTBPGGT1BANPEPENPEP | |
| SCHEMBL8586902 | 0.79 | FNTA (1.00) | FNTAFNTBPGGT1BANPEPENPEP | |
| SCHEMBL1252499 | 0.72 | CFD (0.66) | FNTAFNTBPGGT1BCFD | |
| SCHEMBL31370223 | 0.72 | GRIA2 (0.71) | FNTAFNTBANPEPENPEP | |
| SCHEMBL7996862 | 0.71 | FNTA (0.56) | FNTAFNTBPGGT1BANPEPENPEP | |
| SCHEMBL7994759 | 0.71 | FNTA (0.56) | FNTAFNTBPGGT1BANPEPENPEP | |
| SCHEMBL5862921 | 0.71 | CA1 (0.61) | FNTAFNTBPGGT1BMEP1B | |
| SCHEMBL29276453 | 0.71 | KMO (0.83) | — | |
| SCHEMBL5519447 | 0.70 | KMO (0.63) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011175-A | Inhibition of farnesyltransferase | UNIVERSITY OF PITTSBURGH (US) | 2000-01-04 | — | — | US | disclosed |
| US-5965539-A | PEPTIDOMIMETICS; ANTI-CANCER DRUGS | UNIVERISTY OF PITTSBURGH (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | disclosed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | disclosed |