Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 19/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569163 | 0.88 | RXRA (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7564506 | 0.88 | RXRA (0.46) | PTGS2PTGS1ALOX5 | |
| SCHEMBL8117130 | 0.87 | RXRA (0.45) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7563837 | 0.86 | PTGS2 (0.48) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7561892 | 0.84 | RXRA (0.43) | PTGS2PTGS1ALOX5 | |
| SCHEMBL8106974 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7568206 | 0.76 | ALOX5 (0.39) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7561574 | 0.76 | RXRA (0.60) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7562951 | 0.75 | MAPT (0.39) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7563292 | 0.75 | PTGS2 (0.48) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228055-A1 | DIHYDROAMINOBENZO[B]- AND [C]FURANS AS RETINOID-LIKE AGENTS | Allergan Sales, Inc. (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001012618-A1 | DIHYDROAMINOBENZO[B]- AND [C]FURANS AS RETINOID-LIKE AGENTS | ALLERGAN SALES, INC. (US) | 2001-02-22 | — | — | WO | disclosed |
| US-6093838-A | FOR TREATING SKIN-RELATED DISEASES, INCLUDING ACTINIC KERATOSES, ARSENIC KERATOSES, ECZEMA | ALLERGAN SALES, INC. (US) | 2000-07-25 | — | — | US | disclosed |