SCHEMBL8636609

SCHEMBL8636609

CC(=O)OC(c1cscc1S(=O)(=O)NC(C)(C)C)C(C)F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8641780 0.82
SCHEMBL8111692 0.81 NSD2 (0.36) ALDH1A1HPGD
SCHEMBL8663248 0.76 MAPT (0.32)
SCHEMBL9274694 0.74 GAA (0.48) GAAALDH1A1
SCHEMBL8106979 0.72 ALOX5AP (0.35)
SCHEMBL8641426 0.70 ALDH1A1 (0.34) GAAALDH1A1HPGD
SCHEMBL9021083 0.68 CA12 (0.31)
SCHEMBL8641758 0.67
SCHEMBL9523006 0.66 MAPT (0.37) GAA
SCHEMBL8637568 0.65 NSD2 (0.38) ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726127-A Thiophenesulfonylurea derivatives and herbicidal composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-03-10 US disclosed
EP-0728133-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-08-28 EP disclosed
WO-1995013276-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-05-18 WO disclosed