SCHEMBL9217889

SCHEMBL9217889

CC(=O)OC(F)Cc1ncccc1S(=O)(=O)NC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 8/20 0.37
ALOX5AP P20292 8/20 0.35
FEN1 P39748 8/20 0.35
POLB P06746 2/20 0.35
NSD2 O96028 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9288190 0.83 CA1 (0.38) ALDH1A1
SCHEMBL9523006 0.81 MAPT (0.37) USP30ALOX5APFEN1NSD2
SCHEMBL7806538 0.79 USP30 (0.34) USP30ALOX5APFEN1POLBNSD2
SCHEMBL8106979 0.77 ALOX5AP (0.35) USP30ALOX5APFEN1POLBNSD2
SCHEMBL9217880 0.77 USP30 (0.35) USP30ALOX5APFEN1POLBNSD2
SCHEMBL9020663 0.74 ALDH1A1 (0.35) USP30POLBALDH1A1
SCHEMBL9021100 0.71 USP30 (0.32) USP30POLBALDH1A1
SCHEMBL9259502 0.69 USP30 (0.35) USP30POLBALDH1A1
SCHEMBL9216148 0.68 MMP2 (0.33) ALDH1A1
SCHEMBL8615855 0.68 NSD2 (0.36) USP30ALOX5APFEN1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639190-A1 PYRIDINE SULFONYL UREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-02-22 EP disclosed