Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121966 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8120181 | 0.88 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8114885 | 0.82 | HSD17B10 (0.53) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8116420 | 0.82 | ALDH1A1 (0.55) | ALDH1A1RAB9ASMN1; SMN2HSD17B10MAPK1 | |
| SCHEMBL12830162 | 0.79 | RAB9A (0.43) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8122692 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8124087 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8109297 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8122754 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL8117394 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |