Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097763 | 0.77 | CYP1A2 (0.38) | ALDH1A1TSHRCYP3A4MEN1KMT2A | |
| SCHEMBL4634658 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL3185565 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL5881155 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL11240308 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL18698310 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL6018014 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL8097881 | 0.66 | CYP3A4 (0.34) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL6151901 | 0.65 | RAPGEF4 (0.41) | ALDH1A1TSHRHSD17B10RECQLCYP3A4 | |
| SCHEMBL8097830 | 0.64 | TAAR1 (0.37) | ALDH1A1RECQLMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |