Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112388 | 0.90 | CCR5 (0.39) | CCR5TDP1ATM | |
| SCHEMBL8112453 | 0.89 | CCR5 (0.38) | CCR5 | |
| SCHEMBL9569904 | 0.88 | TDP1 (0.43) | CCR5TDP1ATM | |
| SCHEMBL9137735 | 0.87 | CCR5 (0.43) | CCR5TDP1ATM | |
| SCHEMBL7860693 | 0.81 | TDP1 (0.43) | CCR5TDP1ATM | |
| SCHEMBL7805543 | 0.81 | TDP1 (0.43) | CCR5TDP1ATM | |
| SCHEMBL7811582 | 0.81 | TDP1 (0.43) | CCR5TDP1ATM | |
| SCHEMBL9519179 | 0.81 | TDP1 (0.42) | CCR5TDP1ATM | |
| SCHEMBL9265469 | 0.81 | DPP4 (0.43) | CCR5TDP1ATM | |
| SCHEMBL9521184 | 0.81 | TDP1 (0.42) | CCR5TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |