Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107623 | 1.00 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3HTR1AHTR7 | |
| SCHEMBL3423701 | 0.84 | SLC6A3 (0.66) | SLC6A2SLC6A4SLC6A3HTR1AHTR7 | |
| Bromide SCHEMBL8106532 | 0.79 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR6IRAK4 | |
| SCHEMBL5829723 | 0.75 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL5829382 | 0.74 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL8207336 | 0.74 | SLC6A4 (0.71) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 | |
| SCHEMBL6743669 | 0.73 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 | |
| SCHEMBL6491424 | 0.73 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 | |
| SCHEMBL6709876 | 0.73 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 | |
| SCHEMBL6490964 | 0.73 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107307-A | PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0969005-A1 | Azabicyclic inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |