Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113003 | 0.90 | DNM1 (0.35) | DNM1ALDH1A1TDP1TSHRPLA2G1B | |
| SCHEMBL8114586 | 0.90 | MMP1 (0.31) | MMP1MMP2MMP3MMP8TSHR | |
| SCHEMBL363491 | 0.84 | TSHR (0.33) | DNM1MMP1MMP2MMP3MMP8 | |
| SCHEMBL11872469 | 0.83 | PLA2G1B (0.38) | DNM1TSHRPLA2G1BPLA2G2AFDPS | |
| SCHEMBL8099290 | 0.82 | DNM1 (0.36) | DNM1ALDH1A1TDP1TSHRPLA2G1B | |
| SCHEMBL14638856 | 0.79 | DNM1 (0.44) | DNM1ALDH1A1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL7681683 | 0.77 | DNM1 (0.42) | DNM1ALDH1A1TDP1TSHRPLA2G1B | |
| SCHEMBL8108235 | 0.74 | FDPS (0.36) | FDPS | |
| SCHEMBL7681925 | 0.74 | MMP1 (0.33) | DNM1MMP1MMP2MMP3MMP8 | |
| SCHEMBL4175882 | 0.74 | DNM1 (0.38) | DNM1MMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |