Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 9/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573435 | 0.92 | MAPT (0.42) | GABRG2GABRB3GABRA2GABRA1GABRA5 | |
| SCHEMBL6573021 | 0.90 | ALDH1A1 (0.40) | HSP90AA1HSP90AB1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL6570699 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CYP1A2USP2CYP2D6 | |
| SCHEMBL6572622 | 0.80 | ALDH1A1 (0.42) | GABRG2GABRB3GABRA2GABRA1GABRA5 | |
| SCHEMBL6570805 | 0.78 | CYP1A2 (0.46) | ALDH1A1CYP3A4CYP1A2USP2CYP2D6 | |
| SCHEMBL6571000 | 0.78 | NR3C1 (0.41) | HSP90AA1HSP90AB1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL6572041 | 0.76 | GAA (0.47) | ALDH1A1ALOX15HSD17B10KCNH3MAPT | |
| SCHEMBL6574960 | 0.76 | DHFR (0.38) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL6573372 | 0.74 | MALT1 (0.42) | ALDH1A1CYP3A4CYP1A2USP2CYP2D6 | |
| SCHEMBL6571911 | 0.74 | ALDH1A1 (0.49) | GABRG2GABRB3GABRA2HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |