Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098459 | 0.85 | CYP19A1 (0.30) | — | |
| SCHEMBL7805577 | 0.78 | ECE1 (0.33) | ECE1 | |
| SCHEMBL9795176 | 0.74 | ECE1 (0.38) | ECE1 | |
| SCHEMBL9794941 | 0.74 | ECE1 (0.41) | ECE1 | |
| SCHEMBL8832600 | 0.72 | ECE1 (0.32) | ECE1 | |
| SCHEMBL7811563 | 0.72 | NPSR1 (0.46) | ECE1 | |
| SCHEMBL9215991 | 0.71 | ECE1 (0.34) | ECE1 | |
| SCHEMBL8833259 | 0.71 | ECE1 (0.34) | ECE1 | |
| SCHEMBL8805757 | 0.71 | SIGMAR1 (0.33) | — | |
| SCHEMBL8805750 | 0.71 | SIGMAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |