Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108159 | 1.00 | SLC6A4 (0.44) | SLC6A4HTR1ASLC6A3SLC6A2KDM4E | |
| SCHEMBL14081576 | 0.86 | SLC6A2 (0.46) | SLC6A4SLC6A3SLC6A2KDM4EALDH1A1 | |
| SCHEMBL7464844 | 0.83 | CA12 (0.38) | SLC6A4SLC6A3SLC6A2LMNAHTT | |
| SCHEMBL7464836 | 0.83 | CA12 (0.38) | SLC6A4SLC6A3SLC6A2LMNAHTT | |
| SCHEMBL1021480 | 0.76 | SLC6A3 (0.68) | SLC6A4HTR1ASLC6A3SLC6A2 | |
| SCHEMBL1021477 | 0.76 | SLC6A3 (0.68) | SLC6A4HTR1ASLC6A3SLC6A2 | |
| SCHEMBL6573612 | 0.74 | HTR1A (0.52) | SLC6A4HTR1ASLC6A3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL8108321 | 0.73 | SLC6A4 (0.58) | SLC6A4HTR1ASLC6A3SLC6A2 | |
| SCHEMBL6574406 | 0.73 | HTR1A (0.57) | SLC6A4HTR1ASLC6A3SLC6A2 | |
| SCHEMBL6574408 | 0.73 | HTR1A (0.57) | SLC6A4HTR1ASLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107307-A | PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0969005-A1 | Azabicyclic inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |