Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116397 | 0.91 | MEN1 (0.39) | BRPF1BRD4ALDH1A1LMNATLR9 | |
| SCHEMBL3465161 | 0.89 | ALDH1A1 (0.48) | BRPF1BRD4ALDH1A1LMNAHTR2C | |
| SCHEMBL13682949 | 0.89 | BRPF1 (0.42) | BRPF1BRD4ALDH1A1LMNATLR9 | |
| SCHEMBL3465162 | 0.89 | ALDH1A1 (0.48) | BRPF1BRD4ALDH1A1LMNAHTR2C | |
| Hydrochloric Acid SCHEMBL1639442 | 0.88 | ALDH1A1 (0.50) | BRPF1BRD4ALDH1A1LMNAHTR2C | |
| Hydrochloric Acid SCHEMBL1639438 | 0.88 | ALDH1A1 (0.50) | BRPF1BRD4ALDH1A1LMNAHTR2C | |
| SCHEMBL27660751 | 0.80 | BRPF1 (0.46) | BRPF1BRD4ALDH1A1LMNAHTR2C | |
| SCHEMBL2249055 | 0.80 | BIRC2 (0.46) | BRPF1BRD4ALDH1A1LMNAHTR2C | |
| SCHEMBL12182647 | 0.80 | HTR3E (0.47) | BRPF1BRD4ALDH1A1LMNAHTR2C | |
| SCHEMBL12182691 | 0.80 | HTR3E (0.47) | BRPF1BRD4ALDH1A1LMNAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |