Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14513419 | 0.84 | NLRP3 (0.65) | ALDH1A1HPGDL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL4839353 | 0.84 | PLK1 (0.67) | PLK1ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL2320061 | 0.83 | SMN1; SMN2 (0.77) | PLK1ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL11524084 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1HPGDL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL23944960 | 0.81 | L3MBTL1 (0.66) | ALDH1A1HPGDL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL5086262 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1HPGDL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL9147396 | 0.79 | PLK1 (0.50) | PLK1ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL5720784 | 0.78 | SMN1; SMN2 (0.55) | PLK1ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL10489932 | 0.78 | CYP1A2 (0.59) | PLK1ALDH1A1HPGDL3MBTL1KDM4E | |
| SCHEMBL27685659 | 0.78 | SMN1; SMN2 (0.59) | PLK1ALDH1A1HPGDL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054867-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999036406-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 1999-07-22 | — | — | WO | disclosed |