Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192134 | 0.87 | CYP1A2 (0.71) | L3MBTL1GAAALDH1A1LMNATSHR | |
| SCHEMBL14513419 | 0.84 | NLRP3 (0.65) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL11659268 | 0.84 | ALDH1A1 (0.80) | L3MBTL1GAAALDH1A1LMNATSHR | |
| SCHEMBL21059189 | 0.83 | SMN1; SMN2 (0.68) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL8108517 | 0.81 | PLK1 (0.63) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL11660382 | 0.80 | HPGD (0.70) | L3MBTL1GAAALDH1A1LMNATSHR | |
| SCHEMBL6129365 | 0.80 | CYP1A2 (0.60) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL9423801 | 0.80 | TDP1 (1.00) | L3MBTL1GAAALDH1A1LMNATSHR | |
| SCHEMBL21059187 | 0.79 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL17502667 | 0.78 | KMT2A (0.58) | L3MBTL1GAAALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | L3MBTL1 881/4885GAA 3181/4885ALDH1A1 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.