Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FLI1 | Q01543 | 1/20 | 0.31 |
| ▸ | EWSR1 | Q01844 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100206 | 0.72 | HSD17B10 (0.33) | HPGDSMN1; SMN2HSD17B10KMT2AHTT | |
| SCHEMBL8109706 | 0.70 | PGK1 (0.37) | HPGDSMN1; SMN2HSD17B10KMT2AHTT | |
| SCHEMBL8109917 | 0.69 | KMT2A (0.34) | KMT2ATSHRMEN1 | |
| SCHEMBL3753905 | 0.67 | TRPV4 (0.52) | PGK1CYP11B1CYP11B2 | |
| SCHEMBL8607601 | 0.65 | HPGD (0.40) | HPGDSMN1; SMN2HSD17B10KMT2AHTT | |
| SCHEMBL13593871 | 0.62 | GRM5 (0.35) | — | |
| SCHEMBL3146682 | 0.62 | MCL1 (0.59) | HPGDSMN1; SMN2HSD17B10KMT2AHTT | |
| SCHEMBL21916828 | 0.62 | HPGD (0.41) | HPGDSMN1; SMN2HSD17B10KMT2AHTT | |
| SCHEMBL7867188 | 0.62 | CYP11B1 (0.47) | HPGDSMN1; SMN2HSD17B10KMT2AHTT | |
| SCHEMBL8109821 | 0.62 | CYP11B1 (0.47) | HPGDSMN1; SMN2HSD17B10KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |