Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | HTR1B | P28222 | 5/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9093229 | 0.99 | HTR1A (0.61) | HTR1ASLC6A4DRD2HTR1DHTR1B | |
| SCHEMBL8109878 | 0.84 | HTR1A (0.58) | HTR1ASLC6A4DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9094483 | 0.84 | HTR1A (0.57) | HTR1ASLC6A4DRD2HTR2AHTR2C | |
| SCHEMBL7214578 | 0.76 | HTR1A (1.00) | HTR1ASLC6A4DRD2HTR7 | |
| SCHEMBL14359458 | 0.75 | HTR1A (0.55) | HTR1ASLC6A4HTR7MTNR1A | |
| SCHEMBL8109895 | 0.73 | HTR1A (0.54) | HTR1ASLC6A4DRD2HTR1DHTR2A | |
| SCHEMBL6365007 | 0.73 | HTR1A (0.54) | HTR1ASLC6A4DRD2HTR1DHTR2A | |
| SCHEMBL9408587 | 0.73 | ACHE (0.46) | — | |
| SCHEMBL14359383 | 0.73 | HTR1A (0.56) | HTR1ASLC6A4DRD2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9091527 | 0.72 | HTR1A (0.53) | HTR1ASLC6A4DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669331-B1 | Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-10-11 | — | — | EP | disclosed |
| EP-0669331-A1 | Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-08-30 | — | — | EP | disclosed |