Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | BACE1 | P56817 | 6/20 | 0.46 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109868 | 0.80 | MAP2K4 (0.42) | — | |
| SCHEMBL9408690 | 0.79 | ACHE (0.57) | ACHEBCHE | |
| SCHEMBL8124362 | 0.76 | SLC6A4 (0.56) | — | |
| SCHEMBL1812265 | 0.75 | CCR3 (0.59) | ACHEBACE1BCHECCR3 | |
| SCHEMBL8634398 | 0.74 | MAP2K4 (0.46) | SLC6A3 | |
| SCHEMBL9772634 | 0.74 | HTR3E (0.52) | ACHE | |
| SCHEMBL8108915 | 0.73 | HTR1A (0.62) | — | |
| SCHEMBL23719076 | 0.72 | CCR3 (0.80) | ACHEBCHECCR3 | |
| SCHEMBL6218861 | 0.72 | CCR3 (0.80) | ACHEBCHECCR3 | |
| SCHEMBL8262506 | 0.72 | CCR3 (0.80) | ACHEBCHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348968-A | Migraines | ADIR ET COMPAGNIE (FR) | 1994-09-20 | — | — | US | disclosed |
| EP-0610134-A1 | Indole, indazole and benzisoxazole derivatives as 5-HT1-like agonists | ADIR ET COMPAGNIE (FR) | 1994-08-10 | — | — | EP | disclosed |