Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 19/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120455 | 0.89 | FBP1 (0.74) | FBP1PTPN2PTPN1PTPN5 | |
| SCHEMBL8117894 | 0.84 | FBP1 (0.72) | FBP1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL8119318 | 0.83 | FBP1 (0.78) | FBP1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL8123406 | 0.81 | FBP1 (0.77) | FBP1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL8108185 | 0.80 | FBP1 (0.71) | FBP1 | |
| SCHEMBL8110017 | 0.77 | FBP1 (0.68) | FBP1 | |
| SCHEMBL8126003 | 0.77 | SCN9A (0.44) | — | |
| SCHEMBL5228000 | 0.77 | GPR119 (0.54) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL8124274 | 0.76 | C1R (0.49) | FBP1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL27827052 | 0.76 | FBP1 (0.86) | FBP1HSPD1PTPN2PTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | claimed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | claimed |
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |