SCHEMBL810894

SCHEMBL810894

NC(c1ccccc1)C(NS(=O)(=O)c1cccc(Cl)c1Cl)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGES2 Q9H7Z7 7/20 0.48
ITGAV P06756 2/20 0.47
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 1/20 0.46
PGR P06401 1/20 0.45
NR3C1 P04150 1/20 0.42
ACLY P53396 2/20 0.41
MCOLN3 Q8TDD5 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
CCR4 P51679 1/20 0.38
SLC40A1 Q9NP59 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31702015 0.79 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1PGRACLY
SCHEMBL24541901 0.79 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1PGRACLY
SCHEMBL810061 0.79 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1PGRACLY
SCHEMBL985808 0.79 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1PGRACLY
SCHEMBL3232763 0.78 SLC1A3 (0.56) ITGAVSLC1A3SLC1A2SLC1A1
SCHEMBL7646219 0.78 SLC1A3 (0.56) ITGAVSLC1A3SLC1A2SLC1A1
SCHEMBL14455227 0.78 SLC1A3 (0.40) SLC1A3SLC1A2SLC1A1ACLY
SCHEMBL7526406 0.78 SLC1A3 (0.56) ITGAVSLC1A3SLC1A2SLC1A1
SCHEMBL7613315 0.77 SLC1A3 (0.55) ITGAVSLC1A3SLC1A2SLC1A1
SCHEMBL810628 0.76 ACLY (0.46) ITGAVSLC1A3SLC1A2PGRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399895-B1 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU (JP) 2018-08-08 EP disclosed
US-8558033-B2 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2013-10-15 US disclosed
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL KANTO KAGAKU KABUSHIKI KAISHA (JP) 2011-12-29 US disclosed
EP-2399895-A2 Process for producing optically active aliphatic fluoroalcohol Kanto Kagaku Kabushiki Kaisha (JP) 2011-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL ADH1A, ADH1C, ADH5 PTGES2 3252/4885ITGAV 1273/4885SLC1A3 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.