Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102746 | 0.87 | KMT2A (0.45) | DPP8DPP9KMT2AALDH1A1LMNA | |
| SCHEMBL8102735 | 0.87 | KMT2A (0.45) | DPP8DPP9KMT2AALDH1A1LMNA | |
| SCHEMBL8588975 | 0.87 | KMT2A (0.45) | DPP8DPP9KMT2AALDH1A1LMNA | |
| SCHEMBL8104461 | 0.87 | KMT2A (0.45) | DPP8DPP9KMT2AALDH1A1LMNA | |
| SCHEMBL8104577 | 0.85 | DPP8 (0.36) | DPP8DPP9KMT2AALDH1A1LMNA | |
| SCHEMBL10701426 | 0.84 | RAB9A (0.40) | DPP8DPP9ALDH1A1DPP4DPP7 | |
| SCHEMBL8095107 | 0.83 | KMT2A (0.41) | DPP8DPP9KMT2AALDH1A1LMNA | |
| SCHEMBL8102657 | 0.80 | CCR5 (0.36) | ALDH1A1LMNA | |
| SCHEMBL8095227 | 0.80 | HSD11B1 (0.40) | DPP8DPP9ALDH1A1 | |
| SCHEMBL8095063 | 0.80 | HSD11B1 (0.40) | DPP8DPP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |