Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721513 | 0.82 | KMT2A (0.42) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL1722353 | 0.76 | PDE7A (0.43) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL8109356 | 0.76 | GRM5 (0.43) | KDM4ESMN1; SMN2KMT2AMAPTRAB9A | |
| SCHEMBL12204686 | 0.68 | KMT2A (0.53) | ALDH1A1KMT2ATSHRGAAPOLB | |
| SCHEMBL9837203 | 0.68 | RXFP1 (0.38) | ALDH1A1KMT2AMAPTALPLGAA | |
| SCHEMBL3971941 | 0.67 | KMT2A (0.53) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL18470455 | 0.65 | KMT2A (1.00) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL824417 | 0.64 | RAB9A (0.65) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT | |
| SCHEMBL13957877 | 0.63 | DHODH (0.48) | ALDH1A1KDM4EKMT2ATSHRGAA | |
| SCHEMBL9362074 | 0.63 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121308-A | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBONYLMETHYL) -QUINOLINE-8-SULPHONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM KG (DE) | 2000-09-19 | — | — | US | disclosed |