SCHEMBL824417

SCHEMBL824417

O=C1c2ccccc2-c2nc3ccccc3c(=O)n21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.65
KMT2A Q03164 5/20 0.62
TDO2 P48775 4/20 0.62
IDO2 Q6ZQW0 4/20 0.62
IDO1 P14902 3/20 0.62
NPC1 O15118 2/20 0.62
MAPT P10636 2/20 0.62
LMNA P02545 1/20 0.62
NTRK1 P04629 1/20 0.62
ALOX5 P09917 1/20 0.62
PTGS2 P35354 1/20 0.62
HTT P42858 1/20 0.62
MAPK8 P45983 1/20 0.62
NTRK2 Q16620 1/20 0.62
HDAC6 Q9UBN7 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.52
ALDH1A1 P00352 5/20 0.52
POLB P06746 2/20 0.51
MEN1 O00255 4/20 0.51
APAF1 O14727 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12883999 0.83 RAB9A (0.61) RAB9AKMT2ATDO2IDO2IDO1
SCHEMBL29624740 0.79 RAB9A (1.00) RAB9AKMT2ATDO2IDO2IDO1
SCHEMBL2266526 0.79 RAB9A (1.00) RAB9AKMT2ATDO2IDO2IDO1
SCHEMBL5254527 0.77 ALDH1A1 (0.66) RAB9AKMT2ATDO2IDO2IDO1
Tryptanthrin SCHEMBL2426211 0.77 TDO2 (1.00) RAB9AKMT2ATDO2IDO2IDO1
Tryptanthrin SCHEMBL29359262 0.77 TDO2 (1.00) RAB9AKMT2ATDO2IDO2IDO1
SCHEMBL5248590 0.75 ALDH1A1 (0.63) RAB9AKMT2ATDO2IDO2IDO1
SCHEMBL5246989 0.75 KMT2A (0.78) RAB9AKMT2ATDO2IDO2IDO1
SCHEMBL14571460 0.72 KMT2A (0.80) RAB9AKMT2AMAPTLMNAHTT
SCHEMBL17643209 0.72 MEN1 (0.80) RAB9AKMT2AMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3261759-B1 SELF-HEALING CAPACITOR AND METHODS OF PRODUCTION THEREOF CAPACITOR SCIENCES INC (US) 2020-05-06 EP disclosed
US-10347423-B2 Solid multilayer structure as semiproduct for meta-capacitor CAPACITOR SCIENCES INCORPORATED (US) 2019-07-09 US disclosed
US-RE47117-E1 Compensated in-plane switching mode liquid crystal display CRYSOPTIX K.K. (JP) 2018-11-06 US disclosed
US-20180114641-A1 SOLID MULTILAYER STRUCTURE AS SEMIPRODUCT FOR META-CAPACITOR CAPACITOR SCIENCES INCORPORATED 2018-04-26 US disclosed
US-20180114641-A1 SOLID MULTILAYER STRUCTURE AS SEMIPRODUCT FOR META-CAPACITOR CAPACITOR SCIENCES INCORPORATED 2018-04-26 US disclosed
US-9916931-B2 Energy storage devices and methods of production thereof CAPACITOR SCIENCE INCORPORATED (US) 2018-03-13 US disclosed
US-9916931-B2 Energy storage devices and methods of production thereof CAPACITOR SCIENCE INCORPORATED (US) 2018-03-13 US disclosed
US-9852846-B2 Self-healing capacitor and methods of production thereof CAPACITOR SCIENCES INCORPORATED (US) 2017-12-26 US disclosed
US-9852846-B2 Self-healing capacitor and methods of production thereof CAPACITOR SCIENCES INCORPORATED (US) 2017-12-26 US disclosed
EP-2291703-B1 COLOR LIQUID CRYSTAL DISPLAY AND COMPENSATION PANEL CRYSOPTIX KK (JP) 2016-11-30 EP disclosed
US-20100118241-A1 Liquid Crystal Display Operating in a Vertically Aligned Mode CRYSOPTIX KK (JP) 2010-05-13 US disclosed
WO-2009130676-A2 COLOR LIQUID CRYSTAL DISPLAY AND COMPENSATION PANEL CRYSOPTIX KK (JP) 2009-10-29 WO disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed
WO-2009037565-A2 COLOUR LIQUID CRYSTAL DISPLAY AND PATTERNED COMPENSATION PANEL CRYSOPTIX K.K. (GB) 2009-03-26 WO disclosed
WO-2008142635-A2 COMPENSATED IN-PLANE SWITCHING MODE LIQUID CRYSTAL DISPLAY CRYSOPTIX KK (GB) 2008-11-27 WO disclosed
WO-2007141025-A2 LIQUID CRYSTAL DISPLAY OPERATING IN A VERTICALLY ALIGNED MODE CRYSOPTIX K.K. (JP) 2007-12-13 WO disclosed
WO-2007122389-A2 BACKLIGHT MODULE AND LIQUID CRYSTAL DISPLAY INCORPORATING THE SAME CRYSOPTIX K.K. (JP) 2007-11-01 WO disclosed