Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109750 | 0.80 | MMP1 (0.46) | OGAHRH3 | |
| SCHEMBL20147421 | 0.78 | OGA (0.57) | OGAHRH3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL8025279 | 0.74 | HRH3 (0.69) | HRH3SLC6A4 | |
| SCHEMBL25502660 | 0.73 | OGA (0.53) | OGAEPHX2ALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL6311007 | 0.73 | OGA (0.53) | OGAHRH3CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL7237136 | 0.70 | CHRNB2 (0.55) | OGAEPHX2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL7530388 | 0.70 | CHRNB2 (0.55) | OGAEPHX2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL8395893 | 0.69 | TRPV6 (0.61) | HRH3CHRNB2CHRNA4 | |
| SCHEMBL24308469 | 0.69 | HRH3 (0.68) | HRH3SLC6A4 | |
| SCHEMBL5206162 | 0.69 | HRH3 (0.67) | HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |