Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 4/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | RARG | P13631 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907172 | 0.86 | ATM (0.43) | CYP26A1CYP26B1PKMTSHRATM | |
| SCHEMBL8101913 | 0.85 | RARB (0.53) | CYP26A1CYP26B1RARARARBRARG | |
| SCHEMBL4421853 | 0.83 | KDM4E (0.50) | CYP26A1CYP26B1TSHRATMRARA | |
| SCHEMBL28971883 | 0.81 | CYP26A1 (0.41) | CYP26A1CYP26B1TSHRATMRARA | |
| SCHEMBL6146444 | 0.80 | CYP26A1 (0.50) | CYP26A1CYP26B1TSHRRARARARB | |
| SCHEMBL27557340 | 0.79 | RARB (0.45) | CYP26A1CYP26B1TSHRATMRARA | |
| SCHEMBL9817651 | 0.76 | RARB (0.53) | CYP26A1RARARARBRARG | |
| SCHEMBL7141574 | 0.75 | RARB (0.74) | CYP26A1RARARARBRARGALDH1A1 | |
| SCHEMBL8458478 | 0.75 | RXRA (0.54) | CYP26A1CYP26B1RARARARBRARG | |
| SCHEMBL8459845 | 0.75 | STAT3 (0.62) | RARARARBRARGALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285830-A | Pyridylpyrrole derivatives | SANKYO CO (JP) | 2001-02-28 | — | — | CN | disclosed |
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |