Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.40 |
| ▸ | RARG | P13631 | 4/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109801 | 0.86 | CYP26A1 (0.46) | ATMHPGDRARARARBRARG | |
| SCHEMBL4421853 | 0.84 | KDM4E (0.50) | ATMRARARARBRARGCYP26A1 | |
| SCHEMBL8101913 | 0.84 | RARB (0.53) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL12465802 | 0.83 | RARA (0.56) | ATMHPGDRARARARBRARG | |
| SCHEMBL27557340 | 0.80 | RARB (0.45) | ATMRARARARBRARGCYP26A1 | |
| SCHEMBL28971883 | 0.79 | CYP26A1 (0.41) | ATMHPGDRARARARBRARG | |
| SCHEMBL6146444 | 0.75 | CYP26A1 (0.50) | HPGDRARARARBRARGCYP26A1 | |
| SCHEMBL4945442 | 0.75 | RARA (0.38) | ATMRARARARBRARGCYP26A1 | |
| SCHEMBL4373634 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL9817651 | 0.74 | RARB (0.53) | RARARARBRARGCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |
| US-5476860-A | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD GALDERMA) (FR) | 1995-12-19 | — | — | US | disclosed |
| EP-0514264-B1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-11-15 | — | — | EP | disclosed |
| WO-1992020643-A1 | NOVEL BI-AROMATIC COMPOUNDS DERIVED FROM A SALICILIC PATTERN, METHOD OF PREPARATION AND USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514264-A1 | Biaromatic compounds derived from compounds having a salicylic configuration, their preparation process and their use in human and veterinary medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1992-11-19 | — | — | EP | disclosed |