⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417306 | 0.78 | — | — | |
| SCHEMBL7527333 | 0.78 | — | — | |
| SCHEMBL4276631 | 0.76 | CES2 (0.50) | — | |
| SCHEMBL13590015 | 0.76 | CES2 (0.50) | — | |
| SCHEMBL4456759 | 0.76 | CES2 (0.50) | — | |
| SCHEMBL41570 | 0.76 | CES2 (0.50) | — | |
| SCHEMBL150507 | 0.76 | — | — | |
| SCHEMBL2050459 | 0.76 | — | — | |
| SCHEMBL67123 | 0.76 | CES2 (0.50) | — | |
| SCHEMBL28490272 | 0.75 | CES2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156698-A | The preparation method and purposes of 2- phenyl -1,6- dihydro-pyrimidin -5- formic acid derivates | 沈阳海诺威医药科技有限公司 | 2019-08-23 | — | — | CN | claimed |
| EP-1701949-B1 | ASSAY FOR ENTACTOGENS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2018-04-18 | — | — | EP | claimed |
| CN-107629020-A | A kind of (6H) ketone compounds of 1,2,4 oxadiazines of 4H 5 and its synthetic method | 湖北科技学院 | 2018-01-26 | — | — | CN | claimed |
| CN-107188866-A | A kind of synthetic method of the ketone compounds of polysubstituted thiazole 4 | 湖北科技学院 | 2017-09-22 | — | — | CN | claimed |
| CN-107176925-A | A kind of synthetic method of the cyclohexadione compounds of polysubstituted imidazoline 2,4 | 湖北科技学院 | 2017-09-19 | — | — | CN | claimed |
| CN-107056728-A | A kind of synthetic method of the polysubstituted ketone compounds of 1,2,4 oxygen basudin 5 | 湖北科技学院 | 2017-08-18 | — | — | CN | claimed |
| CN-106966990-A | A kind of synthetic method of the polysubstituted ketone compounds of 2 thiocarbamoyl imidazole quinoline 4 | 湖北科技学院 | 2017-07-21 | — | — | CN | claimed |
| CN-104230826-B | 2 fluoro quinazoline cyclics and preparation method thereof and pharmaceutical usage | 复旦大学 | 2017-03-29 | — | — | CN | claimed |
| CN-105837586-A | Dioxanoquinazoline amine compound and preparation method thereof, and application of dioxanoquinazoline amine compound as epidermal growth factor receptor inhibitor | 北京赛特明强医药科技有限公司 | 2016-08-10 | — | — | CN | claimed |
| CN-104530063-A | Quinazoline and heterocyclic ring compounds, preparing method of compounds, and application of compounds serving as epidermal growth factor receptor inhibitors used for treating cancer | BEIJING DALITAI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-04-22 | — | — | CN | claimed |
| US-20100256139-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2010-10-07 | — | — | US | claimed |
| EP-1979349-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2010-07-28 | — | — | EP | claimed |
| EP-1979349-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | claimed |
| US-20070232645-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2007-10-04 | — | — | US | claimed |
| WO-2007076035-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | claimed |
| JP-3390741-B2 | — | — | 2003-03-31 | — | — | JP | claimed |
| JP-2002500225-A | — | — | 2002-01-08 | — | — | JP | claimed |
| EP-1047694-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-11-02 | — | — | EP | claimed |
| WO-1999035146-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1999-07-15 | — | — | WO | claimed |
| US-4009277-A | 1,2-Dialkyl-3,4,5-trisubstituted pyrazolium salts as fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-22 | — | — | US | claimed |