SCHEMBL67123

SCHEMBL67123

BrC(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
TRPA1 O75762 1/20 0.50
DPP4 P27487 2/20 0.47
F2 P00734 1/20 0.47
TSHR P16473 1/20 0.47
TAAR1 Q96RJ0 2/20 0.43
HTR2A P28223 1/20 0.43
CYP2D6 P10635 1/20 0.41
SRC P12931 1/20 0.41
LMNA P02545 2/20 0.39
HRH1 P35367 1/20 0.39
MTOR P42345 1/20 0.39
RAB9A P51151 1/20 0.39
GRM7 Q14831 1/20 0.39
MAPK1 P28482 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12880577 0.97 CES2 (0.48) CES2CES1TRPA1DPP4F2
SCHEMBL12880591 0.88 CHRNB2 (0.50) CES2CES1TRPA1DPP4F2
Toluene SCHEMBL8412975 0.86 LMNA (0.58) CES2CES1TRPA1DPP4F2
SCHEMBL11576225 0.86 HTR2A (0.58) CES2CES1TRPA1HTR2ALMNA
SCHEMBL8721667 0.86 CHRNB2 (0.54) CES2CES1TRPA1TAAR1HTR2A
SCHEMBL7520122 0.84 LMNA (0.42) CES2CES1TRPA1LMNA
SCHEMBL1528588 0.84 IDO1 (0.54) TRPA1TSHRCYP2D6LMNAMAPK1
SCHEMBL14528562 0.84 CES2 (0.39) CES2CES1TRPA1DPP4F2
SCHEMBL30961545 0.84 PDPK1 (0.42) CES2CES1TRPA1DPP4F2
SCHEMBL10766035 0.84 CES2 (0.39) CES2CES1TRPA1DPP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2656 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3985067-B1 DIAPHRAGM FOR SOUND GENERATING DEVICE AND SOUND GENERATING DEVICE GOERTEK INC (CN) 2025-07-16 EP claimed
WO-2025136243-A1 MECHANOCHEMICAL SYNTHESIS OF HISTAMINE H1-RECEPTOR ANTAGONISTS IHSAN DOGRAMACI BILKENT UNIVERSITESI (TR) 2025-06-26 WO claimed
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP claimed
CN-118307532-A N2 substituted triazole-oxazoline chiral compound and preparation method and application thereof 吉林大学 2024-07-09 CN claimed
CN-117720457-A Manidipine hydrochloride process impurity m-nifedipine and preparation method and application thereof 成都大学 2024-03-19 CN claimed
US-11800288-B2 Diaphragm for sound generating device and sound generating device GOERTEK INC. (CN) 2023-10-24 US claimed
CN-116425650-A Diphenhydramine hapten and artificial antigen as well as preparation methods and applications thereof 华南农业大学 2023-07-14 CN claimed
CN-114805152-B Synthetic method of thioamide 兰州大学 2023-04-14 CN claimed
US-20220360902-A1 DIAPHRAGM FOR SOUND GENERATING DEVICE AND SOUND GENERATING DEVICE GOERTEK INC. (CN) 2022-11-10 US claimed
CN-114805152-A Method for synthesizing thioamide 兰州大学 2022-07-29 CN claimed
WO-1995027745-A1 ETHYLENE α-OLEFIN BLOCK COPOLYMERS AND METHODS FOR PRODUCTION THEREOF EXXON CHEMICAL PATENTS INC. (US) 1995-10-19 WO claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0334511-B1 Oxidation process SOLVAY INTEROX LTD (GB) 1993-10-20 EP claimed
US-5106522-A Liquid hydrophobic vehicle for electro-rheological fluid NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1992-04-21 US claimed
US-4943358-A DIPHENYL METHANES TO BENZOQUINONES, HYDROGEN BROMIDE AND HYDROGEN PEROXIDE INTEROX CHEMICALS LIMITED (GB) 1990-07-24 US claimed
EP-0334511-A2 Oxidation process SOLVAY INTEROX LIMITED (GB) 1989-09-27 EP claimed
EP-0150994-B1 ELECTRO-RHEOLOGICAL FLUID COMPOSITIONS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1987-11-19 EP claimed
EP-0150994-A1 Electro-rheological fluid compositions NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-08-07 EP claimed
US-4332889-A IMPROVED SENSITIVITY, STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-06-01 US claimed
US-4188226-A OXIDIZER, REDUCER, HALOGENATED CARBOCYCLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-02-12 US claimed