Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408587 | 0.80 | ACHE (0.46) | — | |
| SCHEMBL8634398 | 0.73 | MAP2K4 (0.46) | MAP2K4SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL5530480 | 0.72 | — | — | |
| SCHEMBL2997593 | 0.72 | — | — | |
| SCHEMBL7244706 | 0.72 | SPHK2 (0.49) | SPHK2SPHK1 | |
| Ammonia Solution, Strong SCHEMBL29243589 | 0.71 | — | — | |
| SCHEMBL9772634 | 0.70 | HTR3E (0.52) | MAP2K4DRD4 | |
| SCHEMBL8632176 | 0.69 | ALDH1A1 (0.52) | ROCK2 | |
| SCHEMBL27492 | 0.68 | — | — | |
| SCHEMBL15648682 | 0.68 | SPHK2 (0.51) | SPHK2SPHK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669331-B1 | Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-10-11 | — | — | EP | disclosed |
| US-5500443-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |
| EP-0669331-A1 | Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-08-30 | — | — | EP | disclosed |