Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 10/20 | 0.41 |
| ▸ | RARG | P13631 | 9/20 | 0.41 |
| ▸ | RARA | P10276 | 8/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5826295 | 0.88 | MAPT (0.45) | KDM4EMAPTALDH1A1POLBBLM | |
| SCHEMBL8117958 | 0.84 | CYP3A4 (0.36) | KDM4EMAPTALDH1A1POLBBLM | |
| SCHEMBL8458491 | 0.73 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1POLBBLM | |
| SCHEMBL8109768 | 0.73 | KDM1A (0.40) | KDM4EMAPTTDP1MEN1KMT2A | |
| SCHEMBL18144884 | 0.73 | KDM4E (0.42) | KDM4EMAPTALDH1A1POLBBLM | |
| SCHEMBL7698960 | 0.72 | RARB (0.57) | KDM4EALDH1A1POLBBLMCYP2C19 | |
| SCHEMBL8109758 | 0.72 | RARA (0.44) | KDM4EMAPTALDH1A1POLBBLM | |
| SCHEMBL7759522 | 0.71 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1POLBBLM | |
| SCHEMBL17551922 | 0.71 | KDM4E (0.60) | KDM4EMAPTALDH1A1POLBBLM | |
| SCHEMBL18213884 | 0.71 | KDM4E (0.60) | KDM4EMAPTALDH1A1POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285830-A | Pyridylpyrrole derivatives | SANKYO CO (JP) | 2001-02-28 | — | — | CN | disclosed |
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |