Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5826295 | 0.73 | MAPT (0.45) | PGRKDM4EMEN1GAAMAPT | |
| SCHEMBL8109924 | 0.73 | KDM4E (0.47) | KDM1AKDM4EMEN1MAPTKMT2A | |
| SCHEMBL3169552 | 0.73 | SIGMAR1 (0.44) | KDM1AADRA2A | |
| Hydrochloric Acid SCHEMBL27492472 | 0.72 | SIGMAR1 (0.43) | KDM1A | |
| SCHEMBL9843359 | 0.71 | BRD4 (0.36) | KDM1APNMTASIC3PGRBRD4 | |
| SCHEMBL8117958 | 0.68 | CYP3A4 (0.36) | KDM1AKDM4EMEN1MAPTKMT2A | |
| SCHEMBL2223847 | 0.68 | KDM1A (0.43) | KDM1APNMTASIC3BACE1PGR | |
| SCHEMBL5737717 | 0.68 | RARA (0.46) | KDM1ABACE1KDM4EMEN1APAF1 | |
| SCHEMBL8101761 | 0.68 | KDM1A (0.33) | KDM1APNMTASIC3PGRBRD4 | |
| SCHEMBL3115309 | 0.67 | CTSL (0.42) | KDM1APNMTASIC3TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |