Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617511 | 0.88 | CSNK2A1 (0.63) | CSNK2A1MTNR1AMTNR1BHTR1ACYP1A2 | |
| SCHEMBL11617596 | 0.88 | HTR1A (0.61) | CSNK2A1MTNR1AMTNR1BHTR1ACYP1A2 | |
| SCHEMBL8579949 | 0.88 | CSNK2A1 (0.59) | CSNK2A1MTNR1AMTNR1BHTR1ACYP1A2 | |
| SCHEMBL27559060 | 0.80 | MTNR1A (0.60) | MTNR1AMTNR1BHTR1ACYP1A2CYP3A4 | |
| SCHEMBL2727889 | 0.78 | HTR2A (0.62) | CSNK2A1MTNR1AMTNR1BHTR1ACYP2D6 | |
| SCHEMBL2724551 | 0.78 | GPR84 (0.69) | CSNK2A1MTNR1AMTNR1BHTR1ACYP1A2 | |
| SCHEMBL9666304 | 0.78 | HTR2B (0.61) | MTNR1AMTNR1BHTR1ACYP1A2CYP3A4 | |
| SCHEMBL9265645 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BHTR1ACYP1A2CYP3A4 | |
| SCHEMBL7850885 | 0.75 | HTR2A (0.63) | MTNR1AMTNR1BHTR1ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7683721 | 0.74 | NPSR1 (0.64) | MTNR1AMTNR1BHTR1ACYP1A2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114373-A | ADMINISTERING 6-METHOXYMELATONIN TO TREAT FREE RADICAL RELATED DISEASES SUCH AS ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, HEART DISEASE, CANCER, AND TO SLOW THE AGING PROCESS | TAN DUN-XIAN (US) | 2000-09-05 | — | — | US | disclosed |