Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850885 | 0.86 | HTR2A (0.63) | HTR2BMTNR1AMTNR1BHTR1AMPO | |
| Hydrochloric Acid SCHEMBL7683721 | 0.85 | NPSR1 (0.64) | HTR2BMTNR1AMTNR1BHTR1AMPO | |
| SCHEMBL27559060 | 0.84 | MTNR1A (0.60) | HTR2BMTNR1AMTNR1BHTR1AHTR2A | |
| SCHEMBL9265645 | 0.80 | MTNR1A (0.50) | HTR2BMTNR1AMTNR1BHTR1AHTR2A | |
| SCHEMBL8110259 | 0.78 | CSNK2A1 (0.59) | HTR2BMTNR1AMTNR1BHTR1AHTR2A | |
| SCHEMBL27377337 | 0.77 | MPO (0.56) | HTR2BMTNR1AMTNR1BHTR1AMPO | |
| SCHEMBL26602823 | 0.77 | HTR1A (0.79) | HTR2BMTNR1AMTNR1BHTR1AMPO | |
| SCHEMBL31377418 | 0.77 | HTR1A (0.79) | HTR2BMTNR1AMTNR1BHTR1AMPO | |
| SCHEMBL8576847 | 0.77 | KDM4E (0.65) | HTR2BMTNR1AMTNR1BHTR1ACYP1A2 | |
| SCHEMBL3976318 | 0.76 | HTR2B (1.00) | HTR2BMTNR1AMTNR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240352-B1 | 5-FLUOROURACIL DERIVATIVES AND PROCESSES FOR PRODUCING THEREOF | Chisso Corporation (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4792607-A | ANTICANCER MEDICINE INTERRMEDIATES | CHISSO CORPORATION (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0240352-A2 | 5-Fluorouracil derivatives and processes for producing thereof | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |