Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | CCR3 | P51677 | 2/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116069 | 0.93 | CCR3 (0.57) | SIGMAR1CCR3GRIN2BABCB1SLC6A2 | |
| SCHEMBL8958333 | 0.87 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL8114275 | 0.83 | GRIN2B (0.49) | CCR3GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL9449426 | 0.83 | SIGMAR1 (0.57) | SIGMAR1KCNH2 | |
| SCHEMBL8110476 | 0.80 | SIGMAR1 (0.61) | SIGMAR1CCR3GRIN2BABCB1HRH3 | |
| SCHEMBL8109932 | 0.79 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL7756732 | 0.79 | DRD2 (0.45) | SIGMAR1HRH3SLC6A4 | |
| SCHEMBL7756751 | 0.78 | SIGMAR1 (0.44) | SIGMAR1HRH3KCNH2SLC6A2SLC6A4 | |
| SCHEMBL7374609 | 0.77 | SIGMAR1 (1.00) | SIGMAR1CCR3HRH3KCNH2SLC6A2 | |
| SCHEMBL7763028 | 0.76 | SIGMAR1 (0.37) | SIGMAR1HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| US-5534511-A | AFFINITY FOR SIGMA RECEPTORS, ANTIINFLAMMATORY, TREATMENT OF ARTHRITIS | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |